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Mar 31, 2022

TMG (TrimethylGlycine) and Its Importance in the Body

As the name suggests, TMG or trimethylGlycine is the trimethyl derivative of a very common amino acid known as glycine. TMG is more commonly referred to as betaine (as it is more commonly found in our diet in beets other than whole grain, spinach and shellfish).

TMG is naturally made in our body thru the oxidation reaction of choline compounds. Like every other nutrient, if our body doesn’t provide anything sufficiently in a natural way, one needs to take its supplements to avoid any kind of deficiency. TMG supplements too are life savers if our bodies are having a natural deficiency.

Functions of TMG in the Body

TrimethylGlycine is an important nutrient in the human body that has a plethora of essential functions in the body. Let’s take a walk thru those:

  • One of the primary functions of TMG in the human body is to act as an osmolyte. Osmolytic components increase the water retention of the cells preserving the normal hydrated state of the cell.
  • TrimethylGlycine is also a methyl group donor in important metabolic reactions in the body.
  • TMG supplements decrease the risk of heart diseases by lowering the homocysteine levels in the blood.
  • TMG increases muscle strength and enhances exercise performance.
  • It reduces fatigue.
  • It boosts up protein production in the body.
  • TMG helps in the synthesis of creatine. Creatine is the compound that provides energy to the muscle cells.
  • It prevents insulin resistance in the body.
  • It enhances the antidepressant effect of antidepressant drugs.

Mechanism of Action of TMG

  • Donates methyl groups

TrimethylGlycine works in the body by donating one methyl group to homocysteine, thus converting homocysteine to methionine. In this way, it prevents heart diseases. It also serves as an antioxidant by producing S adenosylmethionine.

  • Works as an osmoprotectant for the cells

It keeps cells hydrated, stabilises the membranes due to its osmoprotectant power. TMG also helps to protect the cells from premature cell death.

  • Increase nitric oxide levels

TMG supplements increase nitric oxide levels in the blood, nitric oxide acts as a vasodilator, as a result, increase in blood flow occurs which can ultimately enhance exercise performance.

  • Reduces urine homocysteine levels in homocystinuria patients

It reduces a considerable amount of homocysteine in patients with homocystinuria.

Benefits of TMG Supplement

Still, thinking about why you should use TMG supplements regularly? Let us dive in to know some of the benefits of this heavenly product.

  • Help in Indigestion Problems

TrimethylGlycine supplements create normal acidity levels in the stomach which help in the adequate absorption of nutrients inside the stomach leading to healthier digestion.

  • Helps Cure Fatty Liver

TMG supplements help to prevent the fatty liver by breaking down fatty acids. According to some researchers, it can also help to cure already existing fatty liver disease.

  • Gives a Boost to Muscle Power

TMG promotes muscle protein synthesis, puts on lean mass, accelerates fat loss and thus helps in improving stamina and physical performance as well as muscle recovery. This makes it an all-time favourite for not only bodybuilders and athletes, but also for all others who really want to live their lives to the fullest. It helps the body to lose body fat while gaining muscle mass.

  • Anti-Ageing Effect

Newer studies shed light on its anti-ageing benefits which are of everybody’s interest. Reportedly, it suppresses NF- kappaB which controls the formation of inflammatory molecules. This also aids in the prevention of cancer, arthritis, and atherosclerosis.

How to Use and How Much to Use

Studies confirm that the dose of TMG is 2.5 grammes/ day which is usually taken in 2 equally divided doses: one before and the other after the workout, making it an excellent exercise supplement. So, those of you who are already doing exercise regularly or planning to start a special workout routine may be interested in this special gift straight from heaven because you know that your body is getting what it needs.

Parasympathetic Effect on the Body

TMG takes care of your overall parasympathetic system very well. It balances your body’s autonomic nervous system, especially in people who follow a special nutritional programme or a diet plan.

Results Obtained from Several Experiments

Moving forward in our discussion about the significance of TMG, some of the experiments performed by scientists that show the importance of TMG supplements and their role in the human body will surely encourage you to choose what is best for you and make your mind clear about the importance of using these supplements in your day to day life. Some of the observations and results are as follows:

  • Increased muscle strength in athletes.
  • Increased protein synthesis in people using TMG supplements as compared to the placebo group.
  • Have shown a positive influence on anabolism with decreased cortisol levels.
  • People taking TMG supplements have increased muscle mass, arm size but decreased body fat.

Most of these studies were of 10 to 15 days duration showing that these supplements have rapid effects.

Bottom Line

To sum up, it must be said that if you are into exercises or athletics or just want to boost the functions of your vital organs, you must add this beautiful thing into your daily routine which lets you feel all the new fresh vibes that you need. TMG supplement is a must-have to cope with the modern lifestyle that requires utmost efficiency and effectiveness.




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